This is a very detailed painting of Antwerp how it used to be.
You notice that the centre is very small and all around Antwerp were fields and fields...
You can see how the river bends.
At the bottom right side there was industry.
But they mixed too dangerous things together and one day the whole bunch exploded.
In fact the origin of that explosion was found in the factory where kids had to dismantle unused bullets and bombs etc so they could get recuperate the powder.
Over hundred of children's were killed in an instance, hundreds more injured severely.
The little town was completely blown away from earth and in the city all the windows facing that direction where shattered in little pieces.
Thus came the idea of putting dangerous chemicals etc much further away from the city and safety at factories came to discussion.
Notice that there are NO BRIDGES!!! and ONLY THE RIGHT SITE is populated!
That has several reasons!
First of all the river was always a natural border, the right site used to be Brabant and the left site Flanders.
The left site got flooded very often by the water of the river so it was not suitable to build housed on it.
Only later in time they would succeed to do so.
The river is flowing down on this picture, so leftside is at the right of the drawing and the right side is at the left.
Another reason why the right side developped and had kays where the ships could anker and got loaded and unloaded was because due to the flow of the river and the bends, the right side was hit by the water and deep, while the sand (slib?) was pushed and remained at the left side. That is how developed the Sint Annekes Strand (Saint Anna beach), in former times a local sandy beach. It is still nice to walk there but you can't swim in the water of the Schelde because it is still too poluted.
To highen the capacity of ships small inland wards docks were build (the differen "vliet").
Later real docks with gates where build.
The really first remains were made in the 16th century but it lasted until Napoleon occupied Antwerp that they were made bigger and made real docks.
So the first one is after Napoleon: The Bonapart Dock.