"Van from GUA Antigua Pana to San Cristobal" Guatemala City Transportation Tip by kimanjo
Guatemala City Transportation: 14 reviews and 13 photos
Yes, you can do it, we did it--very common. You can take a shuttle van (or taxi)from GUA to Antigua, then catch another shuttle van to San Cristobal. It is a long journey (full day) but it is done fairly efficiently. The van drivers help you at the border and turn you over to the next van driver, depending upon destination. When we left Antigua we went to the border in a fully-loaded van, and when we got to the border the rest of the group was headed elsewhere, only myself and my husband were going to San Cristobal, so we had the van all to ourselves.
Just Google "van service San Cristobal to Antigua" or something like that and you will get some hits that go to sites with all the details. Good luck--it's fairly cheap.