Don't take warnings of malaria lightly! Kruger National Park, and a few other areas in South Africa are malaria zones and anyone planning to visit should be prepared with the appropriate anti-malarial medication. Whilst the risk is relatively low compared to other parts of Africa, it is real nonetheless, particularly from October to May (the wet season) and anyone planning a visit should be prepared to take the necessary precautions.
See your doctor or a travelller's clinic well before you leave and make sure you have sufficient prophylactic medication for the time you are in a malarial zone. Follow the instructions given carefully. Different prophylactics work in different ways and each one has its own requirements as to how they are to be taken.
Make sure you use a good insect-repellant and take all appropriate measures to avoid being bitten such as covering up (especially around the ankles), particularly in the evening.
Whilst there is no need to be alarmed or to let this put you off, don't listen to anyone who tells you it's not necessary. If they want to take the risk, let that be their decision, but don't mess around with your own health. It only takes one bite!
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Website: http://www.sanparks.org/parks/kruger/tourism/malaria.php