Chronology
4000 - 3000 BC Archaeological findings from the prehistoric sites of Bubanj and Humska Cuka testify that Niš was inhabited as early as in the New Stone Age (Neolithic) and the Early Bronze Age.
2000 BC Several Archaeological sites in the immediate vicinity of Nis reveal prehistoric settlements on Bubanj, in Hum, Gornja and Donja Vrezina, Trupale and Gornja Toponica.
8th century BC Nis area represented the border-zone between the Illyrians and the Thracians.
3rd century BC The Illyrians were defeated by the Celts, who conquered the whole region, and gave Nis its first recorded name: Naissus (The City of Fairies).
75 BC The Nis area was conquered by the Romans during the Dardanian war.
161 AD The first surviving records, by Claudius Ptolomei, in which Nis was mentioned as one of the four biggest cities of Dardania.
2nd century Naissus was an important Roman military centre - a Municipium.
274 Constantine Flavius Valerius was born in Nis.
306 Constantine Flavius Valerius was proclaimed Roman Emperor Constantine the Great.
4th century Ancient Nis, with Constantine's residence at Mediana, flourished in prosperity, as a military and administrative centre of the Roman Empire.
441 Nis was devastated by the Huns, as were many other cities in the Balkans.
1185 Serbian Zupan Stefan Nemanja took over the city of Nis.
1189 In Nis, Stefan Nemanja met Frederick I Barbarossa, the leader of the Crusaders, to discuss the strategy against the Byzantium.
1385 Nis was seized by the Turks for the first time. The siege lasted for 25 days.
1443 In the so-called Long Campaign, Christian armies, led by the Hungarian military leader Janos Hunyadi (known as Sibinjanin Janko in Serbian folk poetry) together with Serbian Despot Djuradj Brankovic, defeated the Turks and repelled them to Sofia. An important battle was fought near Nis, which remained a free city for a whole year after that.
1570 The Dubrovnik colony in Nis was mentioned by German diplomat Rime in his travelogues.
1723 The Nis Fortress was built. It is one of the best-preserved and the most beautiful edifices in the Balkans erected during Turkish rule.
1737 Austrian armies seized Nis for the second time and held it for 85 days
1766 Metropolitan Gavrilo published 'Sindjelija', the first book published here.
1809 The beginning of the Serbian campaign against the Turks. The first battles were fought near Nis.
May 31st 1809 Stevan Sindjelic, Karadjordje's voivoda, led the Nis Campaign army which fought the Turks at Cegar Hill near Nis, and was eventually defeated.
January 11th 1878 Nis was liberated from the Turks. 1878 "Project for the Regulation of Nis", designed by Winter started being applied in Nis town planning. The first Grammar School (Gimnazija) was founded.
1881 The first bank was opened in Nis.
1882 The Teachers' Training College was founded in Nis.
1884. god. The Nis - Belgrade railway line was opened to traffic.The first issue of the local newspapers "Niski vjesnik" was published.
1885 The first hardware workshop was founded. It later grew into the first and the biggest enterprise in the town.